Cosmetological and pharmaceutical composition based on combinatorial quercetin derivative

A method of preparing a combinatorial quercetin derivative, comprising:

• treating quercetin with at least a first alkylating and/or acylating modifier and a second alkylating and/or acylating modifier in a molar ratio of quercetin:
• first modifier:
• second modifier is 92:155:155 to obtain a combinatorial mixture;
• wherein the first alkylating and/or acylating modifier and the second alkylating and/or acylating modifiers are selected from the group consisting of succinic anhydride, acetic anhydride, maleic anhydride, aconitic anhydride, glutaric anhydride, phthalic anhydride, acetic anhydride, formic acid ethyl ester, monochloroacetic acid, propiolactone, ethylene oxide, methyl chloride, ethyl chloride, and propyl chloride.

A method of cosmetological or pharmaceutical treatment, comprising:

• preparing a combinatorial quercetin derivative by treating quercetin with at least a first alkylating and/or acylating modifier and a second alkylating and/or acylating modifier;
• wherein the first alkylating and/or acylating modifier and the second alkylating and/or acylating modifiers are selected from the group consisting of succinic anhydride, acetic anhydride, maleic anhydride, aconitic anhydride, glutaric anhydride, phthalic anhydride, acetic anhydride, formic acid ethyl ester, monochloroacetic acid, propiolactone, ethylene oxide, methyl chloride, ethyl chloride, and propyl chloride;
• wherein a molar ratio of quercetin:
• first modifier:
• second modifier is 92:155:155;
• and
• wherein the resulting combinatorial quercetin derivative is used as a mixture without separating the mixture into individual components;
• preparing an emulsified mixture including the prepared combinatorial quercetin derivative, the emulsified mixture having a composition of:
• 0.5-10 wt. % of the combinatorial derivative of quercetin;
• 50-70 wt. % foaming agent;
• 2-7 wt. % dense extract of chlorophyllipt;
• 1.0-3.0 wt. % cholecalciferol;
• and
• one or more auxiliary substances in an amount to reach a total of 100 wt. %;
• and treating a mammal with the emulsified mixture.