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US 11,229,614 B2Granted
Supramolecular hydrogel applications to the carotid bodies to treat hypertension and sleep apnea in obesity
AssigneeThe Johns Hopkins University
InventorsVsevolod Polotsky, Honggang Cui, Roxana Elena Mitrut, Mi-kyung Shin
Life of this patent
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Abstract
The present invention provides compositions and methods for treating hypertension and obstructive sleep apnea utilizing hydrogel compositions comprising drug amphiphiles with TRPM 7 antagonists for use in a subject, including use on the carotid body of a subject.
Claims4
A composition comprising a drug amphiphile comprising a transient receptor potential melastatin 7 (TRPM7) receptor antagonist and a pharmaceutically acceptable carrier, wherein the drug amphiphile has one of the following formulas:
Dependencies are inferred from the claim text.