Cannabinoid and menthol gel compositions, patches and methods
OwnerBabak Ghalili, Emma Ghaliliinventors
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Abstract
The present disclosure relates to compositions methods of use and methods of manufacturing, hydrous hydrogel compositions useful as topical oral analgesics including cannabinoids and menthol where the menthol component can be a stabilized menthol composition comprising menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid.
Claims20
A transdermal analgesic hydrogel device, comprising:
- a surface to be applied to the skin of a mammal, the surface having an area ranging in size from about 9 cm2 to about 256 cm2;
- water in an amount of from about 70 wt % to about 95 wt %;
- a biocompatible polymer in an amount of from about 0.5 wt % to about 5 wt %;
- a polyalcohol in an amount of from about 1 wt % to about 5 wt %;
- at least one cannabinoid is in an amount of from about 0.1 wt % to about 10 wt %.;
- and
- a stabilized menthol composition comprising a pre-formed mixture of menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid, wherein the therapeutic composition includes menthol in an amount of from about 1 wt % to about 10 wt % and the percentage amounts are all based on the total weight of the transdermal analgesic hydrogel device.
A transdermal analgesic hydrogel patch for topical application to the skin of a mammal, the transdermal analgesic hydrogel patch comprising:
- water in an amount of from about 70 wt % to about 95 wt %;
- carageenan in an amount of from about 0.5 wt % to about 5 wt %;
- glycerin in an amount of from about 1 wt % to about 5 wt %;
- full spectrum hemp oil in an amount of from about 0.1 wt % to about 10 wt %;
- and
- a stabilized menthol composition comprising a pre-formed mixture of menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid, wherein the therapeutic composition includes menthol in an amount of from about 1 wt % to about 10 wt % and the percentage amounts are all based on the total weight of the transdermal analgesic hydrogel patch.
A method of treating pain or inflammation in a body part or portion thereof of a mammal using a transdermal hydrogel patch, the transdermal hydrogel patch including a unit dose formulation comprising:
- water in an amount of from about 70 wt % to about 95 wt %;
- carageenan in an amount of from about 0.5 wt % to about 5 wt %;
- glycerin in an amount of from about 1 wt % to about 5 wt %;
- full spectrum hemp oil in a unit dose amount of from about 2 mg. to about 195 mg;
- and a stabilized menthol composition comprising a pre-formed mixture of menthol and at least one menthol stabilizer compound including undecylenic acid methyl ester, undecylenic acid or a salt of undecylenic acid, wherein the therapeutic composition includes menthol in a unit dose amount of from about 2 mg. to about 400 mg. and the percentage amounts are all based on the total weight of the transdermal hydrogel patch,
- the method comprising topically administering the transdermal hydrogel patch to skin of the body part of the mammal.
Dependencies are inferred from the claim text.