Compositions and methods for selective GI tract delivery
AssigneeVital Beverages Global Inc.
InventorsAmir Barzilay, Dorit Rozner
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Abstract
A composition-of-matter is provided. The present composition includes dietary supplements capable of reducing or reversing the negative effects of alcohol on motor and cognition, dietary supplements having anti-gastroparesis, antiemetic, analgesic and anti-inflammatory activities and/or dietary supplements capable of increasing alcohol catabolism and decreasing the level of toxic products of alcohol catabolism.
Claims16
A composition-of-matter comprising at least two types of microparticles each formed from an active ingredient core encapsulated by two or more coating layers, wherein each coating layer of said coating layers is characterized by a different dissolvability profile, wherein said two or more coating layers comprise an outer coating layer and an inner coating layer, said outer coating layer and inner coating layer comprise a cellulose derivative, said outer coating layer but not said inner coating layer comprises a prolamin, said at least two types of said microparticles being differentiated by said active ingredient or said at least one coating material, wherein said composition comprises the combination of:
- (a) a Serotonin antagonist, (b) a COX inhibitor, (c) a Prostaglandin inhibitor, (d) an upregulator of ADH activity, and (e) an upregulator of ALDH activity, and wherein the ratio of core to said coating (w/w) is between 1:10 and 2:1.
Dependencies are inferred from the claim text.