Process for the manufacture of a solid pharmaceutical administration form
AssigneeMerck Patent GmbH
InventorsStefan Schiller, Andrea Hanefeld, Gerhard Jonschker
Life of this patent
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Abstract
The present invention relates to a process for the preparation of a solid pharmaceutical administration form using a 3D printing process as well. The process is a printing process that allows the production of solid pharmaceutical administration forms in a flexible manner and in conformity with the high quality standards required for the production of pharmaceuticals.
Claims11
A process for the manufacture of a solid pharmaceutical administration form comprising an active ingredient comprising the steps
- (a) spreading a powder comprising a fusible material and an active ingredient across a manufacturing area to create a powder bed;
- (b) jet printing a fluid comprising an energy absorbing material onto the powder;
- (c) irradiating the powder to induce heating of the energy absorbing material in the powder and thereby to induce melting and fusing of the fusible material present in the powder;
- (d) spreading another layer of the powder onto the surface of unfused and fused powder and subsequently performing step (b) and step (c) again;
- (e) optionally repeating step (d) as often as needed to build up the solid pharmaceutical administration form;
- (f) separating the solid pharmaceutical administration form from the powder bed.
A process for the manufacture of a solid pharmaceutical administration form comprising an active ingredient comprising the steps
- (a) spreading a powder comprising an active ingredient across a manufacturing area to create a powder bed;
- (b) jet printing a fluid comprising a fusible material onto the powder;
- (c) irradiating the powder to induce melting and fusing of the fusible material present in the powder;
- (d) spreading another layer of the powder onto the surface of unfused and fused powder and subsequently performing step (b) and step (c) again;
- (e) optionally repeating step (d) as often as needed to build up the solid pharmaceutical administration form;
- (f) separating the solid pharmaceutical administration form from the powder bed.
Dependencies are inferred from the claim text.