Method for determining ischemic status or assessing stroke onset time of a brain region
AssigneeTaipei Medical University
InventorsCheng-Yu Chen, Hsiao-Wen Chung, Duen-Pang Kuo, Chia-Feng Lu, Yu-Chieh Jill Kao
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Abstract
The invention relates to a method for determining ischemic status. The method comprises acquiring magnetic resonance diffusion tensor matrices and obtaining a relative decrease of diffusion magnitude due to the ischemic status from the magnetic resonance diffusion tensor matrices. The invention also relates to a method for assessing stroke onset time. The method comprises acquiring magnetic resonance diffusion tensor matrices and obtaining a relative decrease of pure anisotropy due to stroke from the magnetic resonance diffusion tensor matrices.
Claims15
A method for determining ischemic status of a brain region, comprising:
- acquiring magnetic resonance diffusion tensor matrices of the brain region and of a normal brain tissue, wherein the normal brain tissue and the brain region belong to the same brain tissue type;
- obtaining diffusion magnitude (L) of the brain region (Li) and diffusion magnitude of the normal brain tissue (Ln) from the magnetic resonance diffusion tensor matrices;
- and
- calculating a relative decrease of Li to Ln, and the ischemic status is determined by the relative decrease of Li to Ln;
- wherein the diffusion magnitude L is defined as L=√{square root over (λ12+λ22+λ32)}, wherein λ1, λ2, and λ3 are the eigenvalues of the diffusion tensor matrices, and λ is the mean diffusion;
- and
- the brain region locates in a superficial cortex, a subcortical tissue or a white matter.
Dependencies are inferred from the claim text.