Method for preparing phosphorus-containing α-aminonitriles
AssigneeBASF SE
InventorsKilian Tellmann, Gunter Karig, Heike Ehrich, Michael Sebek
Life of this patent
Estimating the term…
Abstract
The present invention relates primarily to processes conducted in a continuously operated reactor for preparing particular phosphorus-containing α-aminonitriles of the formulae (Ia) and (Ib) defined hereinafter from corresponding phosphorus-containing cyanohydrin esters and to the use thereof for preparation of glufosinate or of glufosinate salts. The present invention further relates to a process for producing glufosinate/glufosinate salts.
Claims20
A process for preparing a mixture comprising at least one compound of the formula (Ia) and at least one compound of the formula (Ib)
- wherein one or more compounds of the formula (II)
- where in each case:
- R2 is (C1-C12)-alkyl, (C1-C12)-haloalkyl, (C6-C10)-aryl, (C6-C10)-haloaryl, (C7-C10)-aralkyl, (C7-C10)-haloaralkyl, (C4-C10)-cycloalkyl or (C4-C10)-halocycloalkyl,
- R5 is (C1-C12)-alkyl, (C1-C12)-haloalkyl, (C6-C10)-aryl, (C6-C10)-haloaryl, (C7-C10)-aralkyl, (C7-C10)-haloaralkyl, (C4-C10)-cycloalkyl or (C4-C10)-halocycloalkyl,
- are converted in a continuously operated reactor while mixing with NH3 in liquid or supercritical form, where the mixing of the compound(s) of the formula (II) and NH3 is effected under the following parameters:
- a mixing time for attainment of a coefficient of variation of 0.10 or less (CoV≤10−1) is less than 30 seconds.
A process for preparing glufosinate
- or glufosinate a salt, wherein, in this process, a mixture comprising at least one compound of the formula (Ia) and at least one compound of the formula (Ib) is used
- where R2 is (C1-C12)-alkyl, (C1-C12)-haloalkyl, (C6-C10)-aryl, (C6-C10)-haloaryl, (C7-C10)-aralkyl, (C7-C10)-haloaralkyl, (C4-C10)-cycloalkyl or (C4-C10)-halocycloalkyl,
- are converted in a continuously operated reactor while mixing with NH3 in liquid or supercritical form, where the mixing of the compound(s) of the formula (II) and NH3 is effected under the following parameters:
- a mixing time for attainment of a coefficient of variation of 0.10 or less (CoV≤10−1) is less than 30 seconds.
Dependencies are inferred from the claim text.