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US 11,219,662 B2Granted
Methods for treating hypotension in a patient that has received an ACE inhibitor by administering angiotensin II
AssigneeLa Jolla Pharma, LLC
InventorsGeorge Tidmarsh, Lakhmir Chawla
Life of this patent
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Abstract
The present disclosure relates to the use of angiotensin II, angiotensin III, or angiotensin IV in therapeutic methods for the treatment of hypotension, especially catecholamine-resistant hypotension.
Claims24
A method of treating hypotension in a human patient that has received an angiotensin converting enzyme inhibitor (ACE inhibitor) within a preceding period of time of up to seven days, comprising:
- administering to the patient a composition comprising angiotensin II, wherein the angiotensin II is administered at an initial rate of 5 ng/kg/min or less, and titrating the rate up or down.
A method of treating hypotension in a human patient that has received an angiotensin converting enzyme inhibitor (ACE inhibitor) within a preceding period of time, comprising:
- determining whether the patient received an angiotensin converting enzyme inhibitor (ACE inhibitor) within a preceding period of time of up to seven days;
- and
- if the patient received an ACE inhibitor within the preceding period of time administering to the patient the composition comprising angiotensin II at an initial rate of 2.5 ng/kg/min.
Dependencies are inferred from the claim text.