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US 11,209,362 B2Granted
Fluorescent probe for detecting sulfenylated protein, preparation method thereof, and application thereof
AssigneeChongqing Medical University
InventorsXiaolei Hu, Xiaolan Yang, Yibing Yin, Xiaomian Wu, Fei Liao, Jinpeng Lu, Juqiong Li
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Abstract
The present invention discloses a fluorescent probe for detecting a sulfenated protein, which has good stability and can specifically quantitatively detect a sulfenated protein in complex biological samples, and has a good detection ability of signal-to-noise ratios, is highly sensitive, and has excellent selectivity, thereby realizing specific detection of sulfhydryl sulfenation modification of intracellular proteins.
Claims6
A fluorescent probe for detecting S-sulfenylated proteins,
- having following formula (I):
- wherein X is a chemical single bond,
- wherein the R is a group selected from the set consisting of
- and R is connected to the NH of X when X is
1 more element
Dependencies are inferred from the claim text.