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US 11,208,736 B2Granted
Methods of generating highly-crystalline recombinant spider silk protein fibers
AssigneeBolt Threads, Inc.
InventorsAmir Ahmad Bakhtiary Davijani, Steven Tom, Maxime Boulet-Audet, Paul Andre Guerette, Lindsay Wray, Nicole Elizabeth Subler, Zoya Nasir Zulfiqar, Hua Li, Jessica Wang
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Abstract
Provided herein are scalable methods of processing wet-spun fiber comprising recombinant spider silk polypeptides to generate a three-dimensional crystalline lattice of beta-sheet structures in the fiber.
Claims23
A drawn fiber comprising a recombinant silk polypeptide comprising SEQ ID NO:
- 1, wherein the fiber is generated by:
- dissolving a powder comprising the recombinant silk polypeptide into a solvent to generate a spin dope, wherein the recombinant silk polypeptide is non-naturally occurring;
- extruding the spin dope into a coagulation bath to form a precursor fiber;
- collecting the precursor fiber without drawing the precursor fiber;
- and
- drawing the precursor fiber over a hot surface to generate a drawn fiber,
- wherein the drawn fiber has a crystallinity index of at least 6% as measured using X-ray diffraction.
4 more elements
Dependencies are inferred from the claim text.