2-carboxypenam compound or salt thereof, pharmaceutical composition containing novel 2-carboxypenam compound or salt thereof, and applications thereof

A compound represented by General Formula [1] or a salt thereof,

• General Formula [1]
• in the formula, R1 represents a hydrogen atom or a carboxyl protecting group;
• R2 represents an aryl group which may be substituted or a heterocyclic group which may be substituted;
• R3 represents a hydrogen atom or a carboxyl protecting group;
• X1 represents a C1-6 alkylene group which may be substituted, a C2-6 alkenylene group which may be substituted, a C2-6 alkynylene group which may be substituted, a divalent cyclic hydrocarbon group which may be substituted, or a divalent monocyclic saturated heterocyclic group which may be substituted;
• A represents a heterocyclic group which may be substituted;
• Q represents a thio group;
• Y1 represents a C1-6 alkylene group which may be substituted, a C2-6 alkenylene group which may be substituted, a C2-6 alkynylene group which may be substituted, a group represented by Formula —N═CH—CH═N—, or a bond;
• X2 represents a group represented by General Formula —NR4— (where, R4 represents a hydrogen atom, a C1-6 alkyl group which may be substituted, or a hydroxyl group which may be protected), a group represented by General Formula —N+R5R6— (where, R5 and R6 are the same as or different from each other and each represent a C1-6 alkyl group which may be substituted, or in combination represent a C2-6 alkylene group which may be substituted or a C2-6 alkenylene group which may be substituted), a group represented by General Formula —NR7—C(═O)—NR8— (where, R7 and R8 are the same as or different from each other and each represent a hydrogen atom, a C1-6 alkyl group which may be substituted, or a hydroxyl group which may be protected), a divalent cyclic amino group which may be substituted, or a bond;
• Y2 represents a C1-6 alkylene group which may be substituted, a C2-6 alkenylene group which may be substituted, a C2-6 alkynylene group which may be substituted, or a bond;
• X3 represents a group represented by General Formula —NR9— (where, R9 represents a hydrogen atom, a C1-6 alkyl group which may be substituted or a hydroxyl group which may be protected) or a bond;
• and
• Y3 represents a group represented by —C(═O)— or —C(═O)—C(═O)—, a group represented by General Formula —C(═O)—C(═NR10)— (where, R10 represents a hydrogen atom, a C1-6 alkyl group which may be substituted, a C1-6 alkoxy group which may be substituted, a C1-6 alkylamino group which may be substituted, a di(C1-6 alkyl)amino group which may be substituted, a cyclic amino group which may be substituted, an amino group which may be substituted, an amino group which may be protected, or a hydroxyl group which may be protected), or a divalent heterocyclic group which may be substituted.