Coordinated multi-prong cancer therapy

A method of providing a coordinated treatment regimen for treating a tumor, comprising:

• reverting an escape phase of the tumor by administering at least a first pharmaceutical composition comprising-a drug that is bound to an albumin, and wherein the drug is selected from the group consisting of Bendamustine, Bortezomib, Cabazitaxel, Chlorambucil, Cisplatin, Cyclophosphamide, Dasatinib, Docetaxel, Doxorubicin, Epirubicin, Erlotinib, Etoposide, Everolimus, Gefitinib, Idarubicin, Hydroxyurea, Imatinib, Lapatinib, Melphalan, Mitoxantrone, Nilotinib, Oxiplatin, Paclitaxel, Pazopanib, Pemetrexed, Rapamycin, Romidepsin, Sorafenib, Vemurafenib, Sunitinib, Teniposide, Vinblastine, Vinorelbine, and Vincristine;
• inducing an elimination phase of the tumor by administering natural killer cells and at least a second pharmaceutical composition comprising an immune stimulatory cytokine, wherein the natural killer cells are selected from the group consisting of aNK cells, haNK cells, and taNK cells, and wherein the immune stimulatory cytokine is selected from the group consisting of IL-2, IL-7, IL-15, IL-17, IL-21, and an IL-15 superagonist;
• maintaining an equilibrium phase of the tumor by administering at least a third pharmaceutical composition comprising a checkpoint inhibitor;
• and
• administering low dose radiation to the tumor.