# US 11,202,906 B2 · Skin treatment device and method for delivery of an active ingredient into the human skin by means of iontophoresis, using an array of electrodes > Agents: this data is available as JSON from the patentgrep API and MCP server — see https://patentgrep.com/llms.txt - Number: US 11,202,906 B2 - Document ID: US11202906B2 - Status: Granted - Kind: B2 - Application number: 16/338,167 - Filed: 2017-09-27 - Published: 2020-01-23 - Granted: 2021-12-21 - Earliest claimed: 2016-09-29 - Assignees: Feeligreen - Applicants: Feeligreen SA - Inventors: Abdelwahhab Yakoub; Christophe Bianchi - Web page: https://patentgrep.com/patent/US11202906B2 ## CPC - A61N 1/325: {for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body (electrodes for external use A61N1/0428)} - A61N 1/0432: {Anode and cathode} - A61N 1/0476: {Array electrodes (including any electrode arrangement with more than one electrode for at least one of the polarities)} - A61N: ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY (measurement of bioelectric currents A61B; surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body A61B18/00; anaesthetic apparatus in general A61M; incandescent lamps H01K; infrared radiators for heating H05B) ## Abstract A skin treatment device, adapted for delivery of an active ingredient into the human skin by means of iontophoresis, the device having electrodes to establish an electric field on the human skin, wherein the device includes an array of n electrodes with at least a first and a second electrode. ## Claims ### Claim 1 Skin treatment device, adapted for delivery of an active ingredient into the human skin by means of iontophoresis, the device having electrodes to establish an electric field on the human skin, wherein the device comprises an array of n electrodes with at least a first and a second electrode, wherein the device is adapted to successively establish an electric field between pairs of electrodes formed by a first electrode and a second electrode of said array of n electrodes, and wherein the device is adapted to form a subsequent pair of electrodes comprising one of the electrodes of a previous pair of electrodes and a further electrode selected from the array of n electrodes, wherein the device is adapted to inverse the polarity of the electrode used in both the previous pair and the subsequent pair prior to establishing an electric field with the subsequent pair of electrodes, wherein the device is adapted to successively form a pair of electrodes with the first and the second electrode of said array of n electrodes, the second and a third electrode of said array of n electrodes, until the pair comprises electrodes n−1 and n, wherein the device is adapted to subsequently form a pair of electrodes with electrode n and the first electrode. ### Claim 2 (depends on 1) The skin treatment device according to claim 1, wherein the electrodes of said array of n electrodes are positioned equidistantly with respect to each other. ### Claim 3 (depends on 1) The skin treatment device according to claim 1, wherein the electrodes are positioned to enclose a surface area. ### Claim 4 (depends on 1) The skin treatment device according to claim 1, wherein the electrodes of the array of n electrodes are positioned to together form a circle. ### Claim 5 (depends on 1) The skin treatment device according to claim 1, wherein the device comprises a control system adapted to provide electrical power to the electrodes in the form of programmable pulses. ### Claim 6 Method for delivering an active ingredient into the human skin by means of iontophoresis, the active ingredient having the form of ions to allow the active ingredient to be introduced into the skin by means of an electric field, wherein the method comprises the use of an array of n electrodes, n being an integer equal to or greater than 3, the array of n electrodes being adapted to be connected to the human skin to apply the electric field to the human skin, the method comprising the following steps: a) selecting a first and a second electrode from said array of n electrodes to form a pair of electrodes and establishing an electric field between the electrodes of said pair of electrodes, said pair of electrodes comprising respectively an anode and a cathode, b) after a determined time period, interrupting the electric field between the electrodes of said pair of electrodes, c) selecting one of the electrodes of a previous pair of electrodes and a further electrode selected from the array of n electrodes, to form a subsequent pair of electrodes, d) inversing the polarity of the electrode used in both the previous pair and the subsequent pair prior to establishing an electric field with the subsequent pair of electrodes and establishing an electric field between the electrodes of the subsequent pair of electrodes, e) after a determined time period, interrupting the electric field between the electrodes of said subsequent pair of electrodes, wherein the method comprises successively forming a pair of electrodes with the first and the second electrode of said array of n electrodes, the second and a third electrode of said array of n electrodes, until the pair comprises electrodes n−1 and n, and then subsequently forming a pair of electrodes with electrode n and the first electrode. ### Claim 7 (depends on 6) The method according to claim 6, wherein the method further comprises: f) repeating steps c), d) and e) for a determined time period. ### Claim 8 (depends on 6) The method according to claim 6, wherein the electrodes are positioned to together enclose a surface area, wherein the method comprises: a′) selecting a first and an adjacent second electrode from said assembly of n electrodes to form a pair of electrodes and establishing an electric field between the electrodes of said pair of electrodes, said pair of electrodes comprising respectively an anode and a cathode, b′) after a determined time period, interrupting the electric field between the electrodes of said pair of electrodes, c′) selecting the second electrode of the pair of electrodes to form the first electrode of a subsequent pair of electrodes and selecting an adjacent electrode to said first electrode of said subsequent pair of electrodes from said array of n electrodes to form the second electrode of said subsequent pair of electrodes, d′) inversing the polarity of the first electrode of the subsequent pair of electrodes and establishing an electric field between the electrodes of said subsequent pair of electrodes, e′) after a determined time period, interrupting the electric field between the electrodes of said subsequent pair of electrodes, and f) repeating step c′), d′) and e′) for a determined time period. ### Claim 9 (depends on 6) The method according to claim 6, wherein the method further comprises: g) controlling the electrical field established between a pair of electrodes by means of programmable electrical pulses.