Control of plant pests using RNA molecules
AssigneeDevgen NV
InventorsYann Naudet, Myriam Beghyn, Lien De Schrijver, Isabelle Maillet, Annelies Philips
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Abstract
Disclosed are double stranded RNA (dsRNA) molecules that are toxic to insect pests. In particular, interfering RNA molecules capable of modulating expression of a pest insect target gene and that are toxic to the insect pest are provided. Further, methods of making and using the interfering RNA, for example as the active ingredient in an insecticidal composition or in a transgenic plant, to confer protection from insect damage are disclosed.
Claims18
A double stranded RNA (dsRNA) molecule comprising a sense strand and an antisense strand, wherein a nucleotide sequence of the antisense strand is complementary to a portion of at least 27 consecutive nucleotides of a mRNA polynucleotide transcribable from a coleopteran insect Rpt5 gene that comprises a Rpt5 coding sequence i) having from at least about 90% identity to at least about 99% identity to SEQ ID NO:7;
- or ii) comprises SEQ ID NO:7, and wherein the dsRNA molecule is toxic to at least a coleopteran insect pest.
Dependencies are inferred from the claim text.