Assembled bioreactor chamber suitable for perfusion culture
AssigneeNanjing Recongene Biomedical Technologies, Inc.
InventorsQing Liu, Xiao Meng
Life of this patent
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Abstract
Provided is an assembled bioreactor chamber comprising an upper end portion, at least one intermediate portion and a lower end portion for forming a chamber of the reactor chamber. The upper end portion and the lower end portion are respectively provided with an interface connected with a culture medium line, and the upper end portion and the intermediate portion, and the intermediate portion and the lower end portion are detachably connected in a sealed manner through a connecting mechanism; when the number of the intermediate portions is ≥2, the adjacent intermediate portions are detachably connected in a sealed manner through a connecting mechanism; and the chamber also comprises a cell carrier for cell attachment growth.
Claims20
An assembled bioreactor chamber suitable for perfusion culture, said bioreactor chamber comprising an upper end portion, one or more intermediate portions and a lower end portion which are successively connected, and said upper end portion, said one or more intermediate portions and said lower end portion forming a chamber of the assembled bioreactor chamber, wherein said upper end portion is provided with an upper end portion interface for connecting with a culture medium line, said lower end portion is provided with a lower end portion interface for connecting with a culture medium line, and the upper end portion and the one or more intermediate portions are detachably connected in a sealed manner, the one or more intermediate portions and the lower end portion are detachably connected in a sealed manner, and when the number of the one or more intermediate portions is ≥2, adjacent intermediate portions are detachably connected with each other in a sealed manner;
- wherein at least one barrier sheet is integrated onto the one or more intermediate portions for changing the flow direction of a culture medium, wherein said assembled bioreactor chamber is a fixed bed bioreactor chamber or a fluidized bed bioreactor chamber.
An assembled bioreactor chamber suitable for perfusion culture, said bioreactor chamber comprising an upper end portion, one or more intermediate portions and a lower end portion which are successively connected, and said upper end portion, said one or more intermediate portions and said lower end portion forming a chamber of the assembled bioreactor chamber, wherein said upper end portion is provided with an upper end portion interface for connecting with a culture medium line, said lower end portion is provided with a lower end portion interface for connecting with a culture medium line, and the upper end portion and the one or more intermediate portions are detachably connected in a sealed manner, the one or more intermediate portions and the lower end portion are detachably connected in a sealed manner, and when the number of the one or more intermediate portions is ≥2, adjacent intermediate portions are detachably connected with each other in a sealed manner;
- wherein at least one barrier sheet is integrated onto the one or more intermediate portions for changing the flow direction of a culture medium, wherein the number of the at least one barrier sheet is equal to or less than the number of the one or more intermediate portions.
Dependencies are inferred from the claim text.