System and method for syringe engagement with injector

A fluid injector comprising an injector housing with at least one syringe port for receiving a syringe, the injector housing comprising:

• a locking mechanism associated with the at least one syringe port for securing the syringe within the at least one syringe port, wherein the locking mechanism is configured for engaging at least one syringe retaining member of the syringe to releasably lock the syringe within the at least one syringe port,
• wherein the at least one syringe retaining member rotationally guides the syringe into self-orienting alignment with the locking mechanism and axially ejects the syringe from the locking mechanism upon rotation of the syringe, and
• wherein the locking mechanism comprises:
• a locking ring disposed within the injector housing, the locking ring rotatable between a first locked position and a second insertion/removal position with rotation of the syringe about a longitudinal axis, the locking ring having a ramp surface configured for interacting with the at least one syringe retaining member of the syringe to rotate the locking ring from the first locked position to the second insertion/removal position, a top surface at a distal end of the ramp surface, the top surface having a first catch and a second catch each protruding distally from the top surface and separated from each other along the top surface, wherein the second catch has a sloped portion.