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US 11,191,850 B2Granted
Molecular probes for detection and imaging of pancreatic cancer
AssigneePortland State University
InventorsRobert M Strongin, Martha Sibrian-Vazquez, Lei Wang, Jorge O. Escobedo Cordova, Mark A. Lowry
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Abstract
Molecular probes for detecting and imaging pancreatic cancer are disclosed. The probes are modified benzoxanthene fluorophores, which are selectively taken up by pancreatic cancer cells, such as pancreatic ductal adenocarcinoma cells. Embodiments of the disclosed probes are useful for pancreatic cancer detection, therapeutic monitoring, and/or image-guided surgery.
Claims14
The probe having a chemical structure according to general formula II
- where R1 is —OCH3 or —NH2.
Dependencies are inferred from the claim text.