Pharmaceutical composition for suppressing cell transplant rejection
AssigneeIndustry-University Cooperation Foundation Hanyang University
InventorsDong Yun Lee, Yong Hwa Hwang, Min Hyung Lee
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Abstract
The present invention relates to a pharmaceutical composition for inhibiting rejection of transplanted cells including a high mobility group box 1 A domain (HMGB1A) as an active ingredient. The use of the pharmaceutical composition can minimize immunological rejection, which may occur upon cell transplantation, and increase the success rate of cell transplantation.
Claims6
A method of inhibiting rejection of transplanted cells comprising a step of pretreating cells prior to transplantation with a pharmaceutical composition comprising a high mobility group box 1 A domain (HMGB1A) combined with a protein transduction domain (PTD) as an active ingredient.
Dependencies are inferred from the claim text.