Method and an apparatus for determining a presence or an amount of a polyamine or its derivative in a sample
AssigneeCity University of Hong Kong
InventorsA. L. Roy Vellaisamy, Chi-Chung Yeung, Shishir Venkatesh, Hon-Wah Lam
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Abstract
A method and an apparatus for determining a presence or an amount of a polyamine or its derivative in a sample, the method including: applying the sample on an electrochemical detector having a substance selection structure, wherein the substance selection structure is sensitive to the polyamine or its derivative; applying at least one voltage bias to the electrochemical detector; and detecting a change of electrical characteristics of the electrochemical detector so as to determine the presence or the amount of the polyamine or its derivative in the sample.
Claims18
An electrochemical apparatus, comprising:
- a substance selection structure including a spermine-specific molecular imprinted polymer layer specifically configured to chemically bind with spermine in a sample;
- and
- an electronic device in electrical connection with the spermine-specific molecular imprinted polymer layer;
- wherein when the sample is in contact with the spermine-specific molecular imprinted polymer layer, the chemical binding of spermine in the sample with the spermine-specific molecular imprinted polymer layer changes an electrical characteristic of the electronic device for indicating presence or an amount of spermine in the sample.
A prostate cancer screening device, comprising:
- a substance selection structure including a spermine-specific molecular imprinted polymer layer specifically configured to chemically bind with urinary spermine in a urine sample of a subject;
- and
- a transistor in electrical connection with the spermine-specific molecular imprinted polymer layer;
- wherein when the urine sample is in contact with the spermine-specific molecular imprinted polymer layer, the chemical binding of urinary spermine in the urine sample with the spermine-specific molecular imprinted polymer layer changes an electrical characteristic of the transistor for indicating presence or an amount of urinary spermine in the urine sample hence a possibility of the subject suffering from prostate cancer.
Dependencies are inferred from the claim text.