Benzenesulfonamide compouds and their use as therapeutic agents

A compound of formula (Ib2):

• as an individual stereoisomer, enantiomer or tautomer thereof or a mixture thereof;
• or a pharmaceutically acceptable salt or solvate thereof, wherein:
• m and n are each 0;
• q is 1, 2 or 3;
• R1 is an optionally substituted aryl, an optionally substituted monocyclic heteroaryl, or an optionally substituted bicyclic heteroaryl;
• R2 is an optionally substituted 5-membered N-heteroaryl or an optionally substituted 6-membered N-heteroaryl;
• R4 and R5 are each hydrogen;
• each R6 is independently alkyl, halo, haloalkyl, cyano, or —OR12;
• R7 is alkyl, alkenyl, halo, haloalkyl, cyano, or —OR12;
• and
• each R8 and R12 is independently hydrogen, alkyl, haloalkyl, optionally substituted cycloalkyl, optionally substituted cycloalkylalkyl, optionally substituted heterocyclyl, or optionally substituted heterocyclylalkyl.