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US 11,173,235 B2Granted
Nitrite eluting devices and methods of use thereof
AssigneeCook Regentec LLC
InventorChad E. Johnson
Life of this patent
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Abstract
The present disclosure generally relates to implantable devices including a releasable nitrite ion and to methods of preparing and using such compositions and devices. In one embodiment, the device is a stent, for example, a vascular stent. In another embodiment, the nitrite ion is ionically bound to an inorganic ion.
Claims16
A medical device comprising:
- a base structure having an external surface and an interior surface, and
- a coating on the external surface comprising a compound comprising an ionically bonded nitrite ion, the nitrite ion being bound in such a way that it is released from the device as a free ion after introduction into a body of a patient, wherein the implantable medical device is free of a nitric oxide generator.
A medical device comprising:
- a vascular stent comprising a base structure having an external surface and an interior surface, and
- a coating on the external surface comprising a compound comprising an ionically bound nitrite ion, the nitrite ion being bound in such a way that it is released from the device as a free ion after introduction into a body of a patient, wherein the implantable medical device is free of a nitric oxide generator and wherein the compound is an inorganic nitrite.
Dependencies are inferred from the claim text.