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US 11,173,022 B2Granted
Liquid applicator for delivering vaccines
AssigneeBoehringer Ingelheim Animal Health USA Inc.
InventorsAurelie de Malibran-Santibanez, Alonso Prado-Masias, Frederic David
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Abstract
The invention relates to a liquid applicator, for administering liquids, including vaccines, to animals. In particular, the applicator is useful for delivering liquids to mouths of animals.
Claims24
An applicator adapted to draw into and deliver a liquid composition to an animal per os, comprising:
- a resilient and/or elongated reservoir defining a longitudinal axis;
- and
- an elongate, hollow stem adapted to be inserted into the animal's mouth,
- wherein the stem comprises a proximal end operably connected to and in fluid communication with the reservoir,
- wherein the stem comprises a distal end adaptable to allow liquid to exit and enter the applicator,
- wherein the stem comprises a first stem region being along the longitudinal axis and a second stem region angled with respect to the longitudinal axis by an angle theta (Θ), which is from about 15 to about 35 degrees,
- wherein the first stem region and the second stem region have a length ratio in a range between 10:1 to 1:10, and
- wherein the applicator is adapted to sealably contain a carrier liquid of the liquid composition to be dispensed to the animal,
- wherein the distal end of the stem is further adaptable to deliver the carrier liquid to a vial containing a lyophilized immunogen such that the liquid composition is formed upon mixing of the carrier liquid with the lyophilized immunogen;
- wherein the distal end is further adaptable to retrieve at least some of the liquid composition from the vial;
- and
- wherein the applicator is adaptable to deliver at least a portion of the retrieved liquid composition to the animal to be vaccinated upon application of pressure to at least a portion of the applicator.
9 more elements
A kit comprising an applicator adapted to deliver a liquid composition to an animal per os and a vial of lyophilized immunogen, wherein the applicator comprises:
- a resilient and/or elongated reservoir defining a longitudinal axis;
- and
- an elongate, hollow stem adapted to be inserted into the animal's mouth,
- wherein the stem comprises a proximal end operably connected to and in fluid communication with the reservoir,
- wherein the stem comprises a distal end adaptable to allow liquid to exit and enter the applicator,
- wherein the stem comprises a first stem region being along the longitudinal axis and a second stem region angled with respect to the longitudinal axis by an angle theta (Θ), which is from about 15 to about 35 degrees,
- wherein the first stem region and the second stem region have a length ratio in a range between 10:1 to 1:10,
- wherein the applicator is adapted to sealably contain a carrier liquid of the liquid composition to be dispensed to the animal,
- wherein the applicator comprises the carrier liquid;
- wherein the distal end is adaptable to deliver the carrier liquid to the vial such that the liquid composition is formed upon mixing of the carrier liquid with the lyophilized immunogen;
- wherein the distal end is further adaptable to retrieve at least some of the liquid composition from the vial;
- and
- wherein the applicator is adaptable to deliver at least a portion of the retrieved liquid composition to the animal to be vaccinated upon application of pressure to at least a portion of the applicator.
10 more elements
Dependencies are inferred from the claim text.