Filter device for capturing target cell and target cell collecting method using the same
AssigneeKorea Institute of Machinery & Materials
InventorsSunghwan Chang, Jung Yup Kim, Hyoun-Hyang Park, Yeong-Eun Yoo
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Abstract
The present invention relates to a filter device for capturing a target cell and a target cell collecting method using the same. A filter substrate by which a target cell is captured is formed of an elastic material. When blood passes, the size of a lattice hole of the filter substrate by which the target cell is captured is reduced. When the blood completely passes, the size of the lattice hole of the filter substrate by which the target cell is captured is restored, so that a destruction rate of the target cell may be reduced and a collect rate of the target cell may be increased.
Claims9
A filter device for capturing a target cell included in a specimen, the filter device comprising:
- a filter substrate formed of an elastic material;
- and
- a plurality of lattice holes arranged in the filter substrate;
- dummy holes disposed on opposing sides of the lattice holes in the filter substrate, wherein the lattice holes are arranged in a line between the dummy holes,
- wherein under application of a pressure to the filter substrate, a structure of the filter substrate is elastically compressed in a first direction in which the lattice holes penetrate the filter substrate or a second direction intersecting the first direction, so that a size of the lattice holes is reduced, and
- wherein the dummy holes do not allow the specimen passing through.
A filter device for capturing a target cell included in a specimen, the filter device comprising:
- a filter substrate formed of an elastic material;
- a plurality of lattice holes arranged in the filter substrate;
- a support substrate installed to be in contact with one surface of the filter substrate;
- and
- a pressing portion installed to press a surface of the filter substrate which is opposite of and faces the one surface,
- wherein under application of a pressure to the filter substrate, a structure of the filter substrate is elastically compressed in a first direction in which the lattice holes penetrate the filter substrate or a second direction intersecting the first direction, so that a size of the lattice holes is reduced,
- wherein
- the lattice holes penetrate the filter substrate in a thickness direction,
- the pressing portion includes:
- a pressing member arranged to face the filter substrate in a face-to-face manner, having an inlet port through which the specimen is injected, and having a spread groove formed on a surface facing the filter substrate;
- and
- a plurality of pressing columns formed on a surface of the pressing member, which faces the filter substrate, and formed to be in contact with upper ends of edge walls of the lattice holes of the filter substrate.
Dependencies are inferred from the claim text.