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US 11,168,052 B2Granted
Carbamate derivative compounds, processes for preparing them and their uses
AssigneeBio-Pharm Solutions Co., Ltd.
InventorYong Moon Choi
Life of this patent
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Abstract
The present invention relates to a pharmaceutical composition for treating or preventing CNS disorders containing a carbamate derivative compound and/or pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or prevention CNS disorders comprising administering a carbamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or prevention of CNS disorders.
Claims16
A compound having the formula 1 or a pharmaceutically acceptable salt thereof:
- wherein,
- R1, R2, R3 and R4 are each independently selected from the group consisting of hydrogen and halogen;
- A and B are each independently selected from the group consisting of
- and —OR7;
- R5 and R6 are each independently selected from the group consisting of hydrogen, C1-C10alkyl, C3-C8cycloalkyl and C6-C10aryl;
- R7 is selected from hydrogen, C1-C10alkyl, C1-C5alkoxyC1-C5alkyl, C6-C10arylalkyloxyC1-C5alkyl, C1-C5alkoxy(C1-C5alkoxy)C1-C5alkyl, C3-C5heterocyclyl, C1-C5alkylthioC1-C5alkyl;
- trialkyl silyl groups and trialkylaryl silyl groups (in trialkyl silyl groups and trialkylaryl silyl groups, each alkyl group is independently selected from the group consisting of linear, branched, or cyclic a C1-C5alkyl groups and each aryl group is independently selected from the group consisting of C6-C10aryl groups);
- and
- l and m are each independently selected from an integer from 0 to 2.
- wherein either of A or B is
- and both A and B cannot be OH at the same time, and when l is 0 and m is 1, or l is 1 and m is 0, one or more of R1, R2, R3 and R4 is halogen.
8 more elements
Dependencies are inferred from the claim text.