Enzymatic production of an acyl phosphate from a 2-hydroxyaldehyde

A method for the enzymatic production of an acyl phosphate, wherein 2-hydroxyaldehyde and phosphate is enzymatically converted to an acyl phosphate by a phosphoketolase, wherein said phosphoketolase is selected form EC 4.1.2.9, EC 4.1.2.22 or any one of SEQ ID NO:1-3 or 16-20, or a sulfoacetaldehyde acetyltransferase (EC 2.3.3.15) according to the following reaction scheme:

• wherein R1 and R2 are selected independently from H, CH3, CH2OH and C2H5 and wherein if R1 is H, R2 cannot be H,
• wherein said method is carried out in an in vitro, cell-free system or by a recombinant microorganism or plant cell overexpressing said phophoketolase or sulfoacetaldehyde acetyltransferase.