Norovirus deactivator and method for producing same, method for deactivating norovirus, method for producing lysozyme component for norovirus deactivation use, prophylactic or therapeutic agent for norovirus infection, and external preparation for skin for norovirus deactivation purposes

A method of deactivating norovirus, the method comprising deactivating norovirus using a norovirus deactivator,

• wherein the norovirus deactivator comprises a lysozyme component that comprises at least one kind selected from the group consisting of a denatured product of a lysozyme and a denatured product of a salt of a lysozyme,
• wherein a total content of the lysozyme component in the norovirus deactivator is 0.05 mass % or more,
• wherein the lysozyme component has a fluorescence intensity of 4,000 or more,
• wherein the fluorescence intensity is a value measurable using a fluorescence spectrophotometer of model FP-8500 from JASCO Corporation, under conditions of an excitation wavelength of 390 nm with an excitation band width of 10 nm, a fluorescence wavelength of 470 nm with a fluorescence band width of 10 nm for a liquid obtained by adding 25 μL of a methanol solution of 8 mM 1,8-anilinonaphthalenesulfonic acid to 5 mL of a dilution obtained by diluting the lysozyme component with a phosphate buffer having a pH of 7.0 so as to have a concentration of the lysozyme component of 0.05 mass % in terms of solid content, and to have a concentration of phosphate of 0.2 M and then subjecting the liquid to a reaction at room temperature for 30 minutes.