Pharmaceutical composition for treating liver cancer, comprising tetraarsenic hexoxide crystalline polymorph
AssigneeChemas Co., Ltd.
InventorsIll Ju Bae, Zenglin Lian
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Abstract
The present invention relates to a pharmaceutical composition for preventing or treating liver cancer and a method for producing same, the composition comprising tetraarsenic hexoxide in which the content of tetraarsenic hexoxide crystalline polymorph a (As4O6-a) is 99% or more. The composition of the present invention exhibits an excellent cancer cell proliferation inhibition effect and thus can be useful as an anticancer drug.
Claims5
A pharmaceutical composition containing tetraarsenic hexoxide (As4O6) as an active ingredient for treatment of liver cancer, wherein the tetraarsenic hexoxide includes 99 wt % or more of tetraarsenic hexoxide crystalline polymorph (a) having features (i) to (iii) below:
- (i) Cell parameters:
- a=b=c=11.0734 Å
- α=β=γ=90°
- V=1357.82 Å3
- (ii) As—O bond length:
- 1.786 Å
- (iii) O—As—O bond angle:
- 98.36°,
- wherein the pharmaceutical composition further comprises at least one of a carrier, a diluent, and an excipient.
Dependencies are inferred from the claim text.