Crafting of cartilage
AssigneeLifeNet Health
InventorsSilvia Sihui Chen, Xiaofei Qin, Jingsong Chen, Lloyd Wolfinbarger, Jr.
Life of this patent
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Abstract
A shaped cartilage matrix isolated from a human or animal where the cartilage has been crafted to facilitate disinfection, cleaning, devitalization, recellularization, and/or integration after implantation. Also, a process for repairing a cartilage defect with the cartilage matrix. The matrix is in the form of an osteochondral plug including a cartilage cap ad subchondral bone, wherein one or more gaps, slats, bores, or channels extend through the tidemark at the interface between the cartilage cap and the subchondral bone.
Claims10
A shaped cartilage matrix isolated from a human or animal, comprising cartilage which is crafted to facilitate disinfection, cleaning, and integration after implantation;
- and wherein said cartilage matrix is isolated from whole condyles, whole plateaus, hemicondyles, hemiplateaus, femoral heads, phalanges, talus, tibia, fibula, rib, intervertebral discs, menisci, nose, or ear,
- wherein said cartilage matrix is in the form of an osteochondral plug;
- wherein said osteochondral plug comprises a cartilage cap and a subchondral bone portion contacting said cartilage cap with a tidemark at an interface between the cartilage cap and subchondral bone portion, said cartilage cap having a superficial surface;
- wherein said osteochondral plug has a straight cylindrical shape, a step cylindrical shape, or a dumbbell shape;
- wherein the subchondral bone portion of said osteochondral plug comprises one or more of gaps, bores, slots, or channels extending through the tidemark into the cartilage cap but not penetrating the superficial surface of the cartilage cap;
- and
- wherein the one or more of the gaps, bores, slots, or channels facilitate disinfection, cleaning, and integration after implantation.
Dependencies are inferred from the claim text.