Anti-dengue virus antibody, pharmaceutical composition comprising the same, and uses thereof
AssigneesNational Cheng Kung University, Dcb-USA LLC
InventorsTrai-Ming Yeh, Yung-Chun Chuang, Yen-Chung Lai
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Abstract
Disclosed herein is an anti-DENV antibody, a pharmaceutical composition comprising the same, and uses thereof. According to embodiments of the present disclosure, the anti-DENV antibody comprises a heavy chain variable region and a light chain variable region, in which the heavy chain variable region comprises amino acid sequences of SEQ ID NOs: 1-3, and the light chain variable region comprises amino acid sequences of SEQ ID NOs: 5-7.
Claims8
A method of treating a dengue virus infection in a subject comprising administering to the subject an effective amount of an antibody, wherein the antibody comprises
- a heavy chain variable region comprising amino acid sequences of SEQ ID NO:
- 1, SEQ ID NO:
- 2 and SEQ ID NO:
- 3;
- and,
- a light chain variable region comprising amino acid sequences of SEQ ID NO:
- 5, SEQ ID NO:
- 6 and SEQ ID NO:
- 7.
Dependencies are inferred from the claim text.