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US 11,142,524 B2Granted
Substituted-3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and stimulator for interferon genes (STING) modulators as cancer immunotherapeutics
AssigneeStingray Therapeutics, Inc.
InventorsHariprasad Vankayalapati, Sunil Sharma, Mohan Rao Kaadige, Alexis Weston, Trason Thode
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Abstract
Substituted -3H-imidazo[4,5-c]pyridine and 1H-pyrrolo[2,3-c]pyridine series of novel Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1) and related compounds, which are useful as inhibitors of ENPP1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the ENPP1.
Claims2
A compound selected from the group consisting of:
- or an isomer or a pharmaceutically acceptable salt thereof.
Dependencies are inferred from the claim text.