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US 11,142,493 B1Granted
Pharmaceutical composition for treating cancer
AssigneeKing Abdulaziz University
InventorsMoustafa E. El-Araby, Abdelsattar M. Omar, Maan T. Khayat, Dhaval Shah, Martin K. Safo, Azizah M. Malebari, Farid Ahmed
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Abstract
Therapeutic compounds containing a phenyl core and amide link(s). Also described are pharmaceutical compositions incorporating the therapeutic compounds and a method for treating cancer with the compounds. These compounds are cytotoxic to stomach, colon, breast, and leukemia cancer cell lines via dual inhibition of Src kinases and tubulin.
Claims3
A pharmaceutical composition having an antiproliferative effect on leukemia cells, stomach cancer cells, breast cancer cells and/or colon cancer cells, comprising:
- at least one compound selected from the group consisting of
- and
- a pharmaceutically acceptable carrier and/or excipient.
Dependencies are inferred from the claim text.