Compositions and methods for degenerative disc regeneration
AssigneeUniversity Health Network
InventorWilliam Mark Erwin
Life of this patent
Estimating the term…
Abstract
There is disclosed herein compositions, methods, uses and systems for reducing pain in a patient that emanates from a body area, preferably spine or joint. Methods of treatment or prevention are described for a disease or condition selected from degenerative disc disease, disc injury, pain, arthritis, or suspected arthritis.
Claims40
A method of treating or preventing the progression of spinal disc degeneration in a subject having degenerative disc disease or a spinal disc injury, the method comprising administering to the subject a composition comprising:
- (i) connective tissue growth factor (CTGF) and/or transforming growth factor beta-1 (TGFβ-1);
- and
- (ii) glucosamine and/or glucosamine hydrochloride.
A method of regenerating spinal disc tissue in a subject having degenerative disc disease or a spinal disc injury, the method comprising administering to the subject a composition comprising:
- (i) connective tissue growth factor (CTGF) and/or transforming growth factor beta-1 (TGFβ-1);
- and
- (ii) glucosamine and/or glucosamine hydrochloride.
A method of inhibiting pain caused by degenerative disc disease or a spinal disc injury in a subject in need thereof, the method comprising administering to the subject a composition comprising:
- (i) connective tissue growth factor (CTGF) and/or transforming growth factor beta-1 (TGFβ-1);
- and
- (ii) glucosamine and/or glucosamine hydrochloride.
A method of preventing the progression of loss of spinal disc height caused by degenerative disc disease or a spinal disc injury in a subject in need thereof, the method comprising administering to the subject a composition comprising:
- (i) connective tissue growth factor (CTGF) and/or transforming growth factor beta-1 (TGFβ-1);
- and
- (ii) glucosamine and/or glucosamine hydrochloride.
Dependencies are inferred from the claim text.