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US 11,141,415 B2Granted
Compositions and kits useful for treatment of respiratory illness
AssigneeThe Procter & Gamble Company
InventorsKelly Lee Martin Schmeichel, Jayant Eknath Khanolkar, Douglas William Gledhill, Susan Elaine Criss, Niranjan Ramji, Elaine Rose Costeines, Thomas Edward Huetter, Radhika R. Iyer, Daren K. Anness
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Abstract
A stable liquid composition in a clear bottle where the composition contains, at least, phenylephrine and acetaminophen. The composition is substantially free of aldehydes and has a pH from 3.5 to 5. The clear bottle is a polyethylene terphthalate bottle.
Claims20
A stable liquid composition in a clear bottle comprising:
- a. from about 0.001% to about 0.5% of phenylephrine hydrochloride, by weight of the stable liquid composition;
- b. one or more additional actives selected from the group consisting of dextromethorphan, acetaminophen, doxylamine, guaifenesin, the free and addition salts thereof, and mixtures thereof, wherein the composition comprises from about 0.0001% to about 10% of total additional actives, by weight of the stable liquid composition;
- c. a flavoring agent comprising one or more non-aldehydic aesthetic agents and mixtures thereof;
- d. a sweetener selected from the group consisting of sugar alcohols, artificial sweeteners, and mixtures thereof;
- wherein the sugar alcohols are selected from the group consisting of glycerin, sorbitol, maltitol, mannitol, and mixtures thereof and the artificial sweeteners are selected from the group consisting of sodium saccharine, acesulfame potassium, sucralose, aspartame, monoammonium glycyrrhizinate, neohesperidin dihydrochalcone, thaumatin, neotame, cyclamates, and mixtures thereof;
- and
- e. a solvent selected from the group consisting of water, propylene glycol, ethanol, and mixtures thereof wherein the composition comprises from about 40% to about 95% of total solvent, by weight of the stable liquid composition;
- wherein the stable liquid composition has a pH of from about 2 to about 6.5;
- wherein the stable liquid composition is a solution;
- wherein the stable liquid composition comprises less than about 0.05% of total aldehydes, by weight of the stable liquid composition;
- and
- wherein the clear bottle comprises a material selected from the group consisting of Polethylene Terephthalate (PET), Glycol-modified Polyethylene Terephthalate (PETG), Oreitned Polypropylene (OPP), Polyvinylchloride (PVC), Polyvinylidene Chloride (PVDC), Nylon, Polyethylene Terphthalate Polyester (PETP), Polyphene, and combinations thereof.
9 more elements
A stable liquid composition in a clear bottle comprising:
- (a) from about 0.01 mg to about 15 mg of phenylephrine hydrochloride, per dose of the stable liquid composition;
- (b) one or more additional actives selected from the group consisting of dextromethorphan, acetaminophen, doxylamine, guaifenesin, the free and addition salts thereof, and mixtures thereof;
- (c) a flavor which comprises one or more non-aldehydic aesthetic agents;
- (d) a sweetener selected from the group consisting of sugar alcohols, artificial sweeteners, and mixtures thereof;
- wherein the sugar alcohols are selected from the group consisting of glycerin, sorbitol, maltitol, mannitol, and mixtures thereof and the artificial sweeteners are selected from the group consisting of sodium saccharine, acesulfame potassium, sucralose, aspartame, monoammonium glycyrrhizinate, neohesperidin dihydrochalcone, thaumatin, neotame, cyclamates, and mixtures thereof;
- (e) a solvent selected from the group consisting of water, propylene glycol, ethanol, and mixtures thereof, wherein the composition comprises from about 40% to about 95% of total solvent, by weight of the stable liquid composition;
- wherein the stable liquid composition is a solution;
- wherein the stable liquid composition has a pH of from about 2 to about 6.5;
- and
- wherein the stable liquid composition comprises less than about 0.05% of total aldehydes, by weight of the stable liquid composition.
7 more elements
Dependencies are inferred from the claim text.