Pharmaceutical composition for preventing or treating aids comprising rhodanine derivative

A method of preventing or treating AIDS, comprising:

• administering, to a subject in need of such prevention or treatment, a nucleoside reverse transcriptase inhibitor (NRTI) and a compound of Formula 1 or a pharmaceutically acceptable salt thereof:
• wherein the NRTI is one or more selected from the group consisting of emtricitabine (FTC), lamivudine (3TC), tenofovir (TFV), a pharmaceutically acceptable salt of any of these, and a prodrug of the tenofovir (TFV),
• wherein the compound of Formula 1 is in an amount of about 2.5 μM, the emtricitabine (FTC) is in an amount of about 5 nM, the lamivudine (3TC) is in an amount of about 1 nM, the tenofovir (TFV) is in an amount of about 0.25 μM, and the prodrug of the tenofovir (TFV) is in an amount which is metabolized into about 0.25 μM of the tenofovir (TFV) after administration, and
• wherein said combination of the NRTI and the compound of Formula 1 yields a greater than additive or synergistic effect as compared to an actually measured virus inhibitory value of each agent alone.