Method of treatment
AssigneeVanda Pharmaceuticals Inc.
InventorsMarlene Michelle Dressman, Mihael H. Polymeropoulos, Paolo Baroldi
Life of this patent
Estimating the term…
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AssigneeVanda Pharmaceuticals Inc.
InventorsMarlene Michelle Dressman, Mihael H. Polymeropoulos, Paolo Baroldi
Estimating the term…
One embodiment of the invention provides a method for administering tasimelteon to a human patient that comprises orally administering an effective dose of tasimelteon under fasted conditions. Fasted conditions may comprise administering the tasimelteon without food, no food at least ½ hour prior to administration, no food at least 1 hour prior to administration, no food at least 1½ hours prior to administration, no food at least 2 hours prior to administration, no food at least 2½ hours prior to administration, or no food at least 3 hours prior to administration. According to such embodiments, tasimelteon may be administered, for example, at a dose of 20 mg/d. Tasimelteon may be administered where, for example, the patient is being treated for a circadian rhythm disorder or for a sleep disorder, including, for example, Non-24 Disorder.
A method of avoiding a delayed Tmax, a decreased Cmax, or both, resulting from the failure to administer tasimelteon without food to a patient suffering from a circadian rhythm disorder or a sleep disorder, the method comprising orally administering to the patient an effective dose of tasimelteon without food, wherein the effective dose is 20 mg/d.
Dependencies are inferred from the claim text.