US 11,141,362 B2 · Nanoemulsions comprising glycerol in aqueous phase

Abstract

The present invention relates to novel oil-in-water nanoemulsions. The oil phase contains oil selected from the group consisting of triglyceride oil and/or petrolatum as well as C8 to C18 fatty acid; and the aqueous phase contains specific N-acyl derivatives having specific counterions of amino acid salt as emulsifier, glycerol, and water. When (i) there is defined ratio of glycerol to water; (ii) specific counterion for amino acid surfactant and (iii) fatty acid in oil phase. Nanoemulsions are processed in a one-step process yielding droplets of size 20 to 400 nm. In one embodiment, droplets of size 20 to 400 nm can be made using rotor-stator device (in one-step process) and in the absence of pressure based homogenizer. This saves in energy and cost. Compositions prepared according to this processes are also contemplated.

Claims14

Dependent claims

A nanoemulsion composition comprising:

a) an internal phase comprising (1) 40 to 75% by wt. of total nanoemulsion composition of oils selected from the group consisting of triglyceride, petrolatum and mixtures thereof, wherein the melting point of the petrolatum is 30 to 60° C.;
and (2) 1.5 to 10% by wt. nanoemulsion of a C8 to C18 fatty acid;
and
b) an external aqueous phase comprising:
i. 2 to 12% by wt. as active of total nanoemulsion composition of a surfactant or surfactants which are N-acyl derivatives of amino acid salt;
wherein the surfactant of (i) comprises 65% or greater of trialkanolamine or potassium salts or mixtures thereof of said surfactant;
ii. glycerol, and
iii. water
wherein the weight ratio of glycerol to water in aqueous phase is 3:1 to 1:3;
and
wherein the volume average diameter of droplets of (a) is 20 to 400 nanometers.

8 more elements

Dependencies are inferred from the claim text.

Nanoemulsions comprising glycerol in aqueous phase

Life of this patent

Nanoemulsions comprising glycerol in aqueous phase

Life of this patent

Abstract

Claims14