Method and device for localized intravascular therapy

A non-occlusive intravascular device for local application of a therapeutic agent to a lumenal wall of a blood vessel at a selected site within the vessel, the device comprising:

• a catheter having a distal end and a proximal end;
• a radially expandable/collapsible flexible scaffold circumferentially connected around a distal portion of said catheter extending between a first location and a second location on said distal portion, wherein said scaffold has an open-skeletal structure and a flexible outer surface capable of conforming to the lumenal wall at the selected site without applying a radial force thereon, and wherein said therapeutic agent is loaded on the outer surface of the scaffold;
• a controllable mechanism for expanding and collapsing said scaffold;
• a plurality of touch sensors distributed on the outer surface of said scaffold, configured to detect contact with the lumenal wall;
• and
• a control unit;
• wherein said touch sensors and said controllable mechanism are in communication with said control unit;
• and
• wherein said control unit is programmed to:
• collect and process data from the touch sensors;
• control expansion of said scaffold in accordance with the processed data;
• and
• prevent further expansion of the scaffold and provide an indication when optimized deployment of the scaffold is achieved.