Method and system for determining a risk of cardiac conduction abnormalities

A method for determining a measure of a risk of a patient developing cardiac conduction abnormalities as a result of transcatheter structural heart intervention, the method comprising:

• providing a patient-specific anatomical model representing a patient-specific cardiac region, the patient-specific anatomical model comprising a finite element mesh;
• providing an implant model representing a finite element representation of a cardiac implant;
• virtually placing the implant model into the patient-specific anatomical model;
• determining, from the virtually placed implant model into the patient-specific anatomical model, a measure of mechanical interaction between the implant model and the patient-specific anatomical model;
• determining a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction;
• and
• estimating a position of a conduction system in the patient-specific anatomical model.

A system for determining a measure of a risk of a patient developing cardiac conduction abnormalities as a result of transcatheter structural heart intervention, the system comprising a processor, the system configured to:

• receive a patient-specific anatomical model representing a patient-specific cardiac region, the patient-specific anatomical model comprising a finite element mesh;
• receive an implant model representing a finite element representation of a cardiac implant;
• virtually place the implant model into the patient-specific anatomical model;
• determine, from the virtually placed implant model into the patient-specific anatomical model, a measure of a mechanical interaction between the implant model and the patient-specific anatomical model;
• and
• determine a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction,
• wherein to virtually place and to determine the measure of risk comprise virtually place the implant model into the patient-specific anatomical model at a plurality of different locations and determine the measure of the risk of the patient developing cardiac conduction abnormalities for each of the different locations.

A non-transient computer-readable medium comprising computer implementable instructions which when implemented by a programmable computer cause the computer to:

• retrieve a patient-specific anatomical model representing a patient-specific cardiac region, the patient-specific anatomical model comprising a finite element mesh;
• retrieve an implant model representing a finite element representation of a cardiac implant;
• virtually place the implant model into the patient-specific anatomical model;
• determine, from the virtually placed implant model into the patient-specific anatomical model, a measure of a mechanical interaction between the implant model and the patient-specific anatomical model;
• and
• determine a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction,
• wherein to virtually place and to determine the measure of risk comprise virtually place the implant model into the patient-specific anatomical model at a plurality of different locations and determine the measure of the risk of the patient developing cardiac conduction abnormalities for each of the different locations.

A system for determining a measure of a risk of a patient developing cardiac conduction abnormalities as a result of transcatheter structural heart intervention, the system comprising a processor, the system configured to:

• retrieve a patient-specific anatomical model representing a patient-specific cardiac region, the patient-specific anatomical model comprising a finite element mesh;
• retrieve an implant model representing a finite element representation of a cardiac implant;
• virtually place the implant model into the patient-specific anatomical model;
• determine, from the virtually placed implant model into the patient-specific anatomical model, a measure of mechanical interaction between the implant model and the patient-specific anatomical model;
• determine a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction;
• and
• estimate a position of a conduction system in the patient-specific anatomical model.

A non-transient computer-readable medium comprising computer implementable instructions which when implemented by a programmable computer cause the computer to:

• retrieve a patient-specific anatomical model representing a patient-specific cardiac region, the patient-specific anatomical model comprising a finite element mesh;
• retrieve an implant model representing a finite element representation of a cardiac implant;
• virtually place the implant model into the patient-specific anatomical model;
• determine, from the virtually placed implant model into the patient-specific anatomical model, a measure of mechanical interaction between the implant model and the patient-specific anatomical model;
• determine a measure of risk of the patient developing cardiac conduction abnormalities on the basis of the determined mechanical interaction;
• and
• estimate a position of a conduction system in the patient-specific anatomical model.