Device for cell spraying
AssigneeRenovaCare Sciences Corp.
InventorReinhard Bornemann
Life of this patent
Estimating the term…
Abstract
The invention provides a description of a method and a device suitable for producing a cell suspension spray with living cells, and the produced cell preparation, suitable for grafting to a patient. In contrast to other methods, the spraying is performed through a disposable needle which is inserted into a disposable air tube; which provides a cell distribution avoiding spray nozzles. Small suspension droplets are provided instead of cell nebulization. By using medical grade sterile Luer-lock disposables from medical routine praxis, biocompatibility and easy application is addressed. In applying the method and/or in using the device, cells suitable for grafting to a patient are dispersed in a solution and sprayed with the device for distribution over the recipient graft site.
Claims23
A device for spraying a biologically compatible liquid, a biologically compatible suspension, or a cell suspension, the device comprising:
- a component having a support portion configured to receive a container, the container releasably storing the biologically compatible liquid, the biologically compatible suspension, or the cell suspension;
- a handle coupled to the component;
- a hollow needle configured to be removably coupled to the container when the container is received in the component;
- a tube configured for connection to the hollow needle and connection to a gas source to deliver a gas stream through and out the tube;
- and
- an actuator that engages the container when the container is received in the component to push the biologically compatible liquid, the biologically compatible suspension, or the cell suspension out of the container and out through the needle,
- wherein the needle is disposed inside a portion of the tube such that the biologically compatible liquid, the biologically compatible suspension, or the cell suspension is injected into the gas stream and sprayed from an end of the tube as suspension droplets, and
- wherein at least one of the needle and the tube are disposable.
A multi-part device for cell spraying, the multi-part device comprising:
- a component having a support portion configured to receive a disposable syringe, the disposable syringe releasably storing a cell suspension;
- a disposable hollow needle configured to be secured within a needle path of the component, the disposable hollow needle releasably attached to the syringe when the syringe is received in the component;
- a disposable tube configured to be secured within a tube path of the component, the disposable tube having a first end and a second end, the disposable tube configured to releasably connect to a gas source at the first end to deliver a gas stream through the tube and out the second end;
- and
- an actuator connected to the syringe when the syringe is received in the component to push the cell suspension out of the syringe and out through the needle,
- wherein the needle intersects the tube at a location between the first end and second end of the tube such that the needle is contained within a portion of the tube, and the cell suspension is injected into the gas stream and sprayed from the second end of the tube.
A method of spraying a biologically compatible liquid, a biologically compatible suspension, or a cell suspension through a multi-part device, the method comprising:
- securing a disposable syringe in a support portion of the multi-part device, the disposable syringe releasably storing the biologically compatible liquid, the biologically compatible suspension or the cell suspension;
- securing a disposable needle in the support portion of the multi-part device;
- attaching the disposable needle to the disposable syringe;
- securing a disposable tube in the support portion of the multi-part device, the disposable tube having a first end and a second end, the first end connected to a gas source;
- delivering a gas stream from the gas source through the disposable tube and out the second end;
- pushing the biologically compatible liquid, the biologically compatible suspension or the cell suspension out of the disposable syringe and out through the needle,
- injecting the biologically compatible liquid, the biologically compatible suspension, or the cell suspension exiting the needle into the gas stream exiting the tube to form suspension droplets,
- wherein a portion of the disposable needle is contained inside a portion of the disposable tube.
Dependencies are inferred from the claim text.