Process for lyophilising a product
Assignee4D Pharma LeóN S.L.U.
InventorsChristophe Carite, Sophie Declomesnil
Life of this patent
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Abstract
The present invention relates to a process for lyophilising a product (3), comprising the steps of providing a bulk product (3) loading system in the form of a bag (1), the bag (1) having an interior and an exterior defined by a flexible wall, the bag (1) further comprising a filling port (5) providing access to the interior of the bag (1), filling a product (3) having a first moisture content into the interior of the bag (1) via the filling port (5), and exposing the product (3) in the interior of the bag (1) to a lyophilisation cycle such that the moisture content of the product (3) is reduced from the first moisture content to a second, lower, moisture content.
Claims17
A method for lyophilizing a product comprising:
- a. filling a product into an interior of a bag comprising a filling port configured to provide access to the interior of the bag, wherein the interior of the bag is defined by two substantially coplanar flexible walls spaced apart by a side wall when filled, and wherein the product comprises pharmaceutical-grade live anaerobic bacterial cells having a first moisture content;
- and
- b. exposing the product to a lyophilization cycle in a lyophilizer via a portion of the bag which is open, wherein the first moisture content of the product is reduced to a second moisture content.
Dependencies are inferred from the claim text.