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US 11,130,777 B2Granted
Crystalline phases of 5,6-dichloro-2-(isopropylamino)-(1-beta-L-ribofuranosyl)-1H-benzimidazole
AssigneeTakeda Pharmaceutical Company Limited
InventorsGerard Coquerel, Guillaume Levilain, Marie-Noelle Petit, Servane Coste-Leconte
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Abstract
The invention relates to novel crystalline phases of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole (Maribavir), pharmaceutical compositions thereof and their use in medical therapy.
Claims20
A composition comprising an admixture of a crystalline form VI solvate of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole and a crystalline form VII of 5,6-dichloro-2-(isopropylamino)-1-(β-L-ribofuranosyl)-1H-benzimidazole, wherein the crystalline form VI solvate comprises an organic solvent selected from the group of:
- ethyl acetate and diethylether.
Dependencies are inferred from the claim text.