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US 11,125,758 B2Granted
Methods and kits for detecting misfolded proteins
AssigneesYale University, The Regents of the University of California
InventorsCatalin S. Buhimschi, Irina Buhimschi, Charles G. Glabe
Life of this patent
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Abstract
Methods, kits and compounds are provided that relate to the diagnosis, treatment, and/or prevention of preeclampsia.
Claims10
A method comprising:
- combining a urine sample obtained from a female subject with an A11 antibody that binds specifically to soluble pre-amyloid oligomers;
- and
- assaying the sample for the presence or absence of the A11 antibody bound to soluble pre-amyloid oligomers.
A method comprising:
- combining a placental sample obtained from a female subject with an OC antibody that binds specifically to amyloid fibrils;
- and
- assaying the sample for the presence or absence of the OC antibody bound to amyloid fibrils.
Dependencies are inferred from the claim text.