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US 11,123,434 B2Granted
Drug delivery device and its method of manufacture
AssigneeCity University of IIong Kong
InventorsWing Fu Lai, Andrei Rogatch
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Abstract
The invention relates to a drug delivery device adapted for carrying and delivering both hydrophilic and lipophilic drug molecules. The drug delivery device includes a porous body for adsorption of drug molecules, the body including a plurality of microspheres, and a hydrogel forming cross-links connecting the plurality of microspheres.
Claims9
A method of producing a drug delivery device, comprising:
- mixing target molecules in the form of where R is trimethylolpropane ethoxylate triacrylate, and initiator molecules to form an emulsion;
- and
- curing the emulsion using ultraviolet light or corresponding energy source, with the aid of the initiator molecules, to form, in a one-pot process, a microsphere hydrogel sponge with a porous body,
- the porous body being adapted for adsorption of drug molecules, wherein the porous body comprises:
- a plurality of poly(trimethylolpropane ethoxylate triacrylate) microspheres, and
- a hydrogel comprising the target molecules being cross-linked together in the form of
- and forming cross-links connecting the plurality of poly(trimethylolpropane ethoxylate triacrylate) microspheres.
4 more elements
Dependencies are inferred from the claim text.