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US 11,123,316 B2Granted
Imaging composition and uses thereof
AssigneeThe University of Melbourne
InventorsPaul Stephen Donnelly, Stacey Erin Rudd, Spencer John Williams
Life of this patent
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Abstract
The invention discussed in this application relates to hydroxamic acid-based compounds that are useful as imaging agents when bound to an appropriate metal centre, particularly for the imaging of tumours.
Claims17
A pharmaceutical composition comprising a radionuclide-labelled conjugate of:
- a compound of formula (I):
- or a pharmaceutically acceptable salt thereof, wherein L is a leaving group selected from azide, halogen, cyanate, and OR, wherein R is selected from C1 to C10 alkyl, C1 to C10 heteroalkyl, C2 to C10 alkene, C2 to C10 alkyne, and aryl, each of which is optionally substituted,
- a molecule to target a tissue or tumour, and
- a radionuclide complexed thereto,
- and one or more pharmaceutically acceptable carrier substances, excipients and/or adjuvants.
2 more elements
Dependencies are inferred from the claim text.