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US 11,117,878 B2Granted
Benzothiazole and related compounds
AssigneeSpinogenix, Inc.
InventorsStella Sarraf, Vincent F. Simmon, Gerald F. Swiss
Life of this patent
Estimating the term…
Abstract
Disclosed are compounds that promote spinogenesis, are capable of reducing the neural toxicity of beta-amyloid peptides, and/or reduce the symptoms of traumatic brain injury in a patient.
Claims18
A compound according to Formula VII:
- or a pharmaceutically acceptable salt or solvate thereof, wherein:
- subscripts n and p are each independently 0, 1 or 2;
- subscript q is 4;
- and
- each R1 and each R2 are independently selected from the group consisting of halo, alkyl, substituted alkyl, alkenyl, substituted alkenyl, alkoxy, substituted alkoxy, acyl, acylamino, aminocarbonyl, aminosulfonyl, amino, substituted amino, aryl, substituted aryl, carboxyl, carboxyl esters, cyano, cycloalkyl, substituted cycloalkyl, heteroaryl, substituted heteroaryl, heterocyclyl, substituted heterocyclyl, hydroxyl, sulfonyl, substituted sulfonyl, thiol, thioalkyl, and nitro.
2 more elements
A compound, or a pharmaceutically acceptable salt or solvate thereof, having the formula:
Dependencies are inferred from the claim text.