Terpineol and preparation method and application thereof
AssigneeZhejiang Academy of Traditional Chinese Medicine
InventorsWanping Zhu, Yongzhou Hu, Xia Liu, Fanzhi Kong, Yuji Wang
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AssigneeZhejiang Academy of Traditional Chinese Medicine
InventorsWanping Zhu, Yongzhou Hu, Xia Liu, Fanzhi Kong, Yuji Wang
Estimating the term…
The present invention discloses a terpinenol compound as well as its preparation method and application. The structure of such terpinenol compound is as shown in Formula (I) or (II). In Formula (I), R is independently selected from C12-C16 alkyl, —NR1R2, —SR3 or —OR4; R1, R2, R3 and R4 are independently selected from C1-C6 alkyl or —NO2; the C1-C6 alkyl can be substituted by OH; Alternatively, the R1 and R2 form a five-member ring or six-member ring in together with N used to link up them; the five-member or six-member ring may contain one O or C═O. As indicated by results of activity test, such terpinenol compound has satisfactory effect in prevention of asthma, inflammation and pulmonary artery hypertension, which also has high pharmaceutical significance.
A terpinenol compound, characterized in that its structure is as shown in Formula (I):
A method of treating or alleviation of asthma, inflammation or pulmonary hypertension in a subject comprising the step of administering an effective amount of a terpinenol compound to the subject;
Dependencies are inferred from the claim text.