Assay device, system, method, and kit

An assay device for detection of an analyte in a bodily fluid sample, the assay device comprising:

• a fluid sample collector, including:
• a cap;
• a plunger carried by the cap and having a distal end;
• an absorbent member supported toward the distal end of the plunger;
• and
• an assessment unit to which the fluid sample collector couples, including:
• a sample-receiving chamber having at least one sidewall, a fluid outlet, and an opening through which the plunger and absorbent member are received within the sample-receiving chamber, the plunger and the at least one sidewall being closely sized such that pressure is increased within the sample-receiving chamber as the plunger is advanced toward the outlet;
• a fluid filter across the outlet;
• a well in fluid communication with the outlet to receive fluid sample filtrate therefrom;
• at least one test panel in fluid communication with the well, the at least one test panel providing an indication when contacted by an analyte in the filtrate;
• helical threads on the cap and the assessment unit which removably couple the cap to the assessment unit closing the opening, the threads further having a pitch converting rotational force to linear force to advance the plunger axially within the sample-receiving chamber as the cap is rotated to create a differential pressure across the filter driving the fluid sample therethrough and the filtrate into the well, the axial advancement of the plunger being controlled by the pitch of the threads;
• and
• a window through which the indication is viewed.