# US 11,112,301 B2 · Method for correcting optical sensor array module through characteristic evaluation

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- Number: US 11,112,301 B2
- Document ID: US11112301B2
- Status: Granted
- Kind: B2
- Application number: 15/577,586
- Filed: 2016-06-09
- Published: 2018-06-14
- Granted: 2021-09-07
- Earliest claimed: 2015-06-09
- Assignees: Sol Inc.
- Applicants: Sol Inc.
- Inventors: Jong Muk Lee; Tae Young Lee; Jae In Kim
- Web page: https://patentgrep.com/patent/US11112301B2

## CPC

- G01J 1/44: Electric circuits {(for command of an exposure part G03B7/02)}
- G01N 21/6428: {Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" (in vivo A61B5/00; immunoassay G01N33/53)}
- G01N 21/6458: {Fluorescence microscopy (fluorescence microscopes per se G02B21/0076 and G02B21/16)}
- H04N 25/671: for non-uniformity detection or correction
- H04N 25/672: between adjacent sensors or output registers for reading a single image
- H04N 25/673: by using reference sources
- H04N 25/76: Addressed sensors, e.g. MOS or CMOS sensors
- H10F 39/12: Image sensors
- G01J 2001/444: {Compensating; Calibrating, e.g. dark current, temperature drift, noise reduction or baseline correction; Adjusting}
- G01N 2201/062: LED's
- G01J: MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY (light sources F21, H01J, H01K, H05B; investigating properties of materials by optical means G01N)
- G01N: INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES (measuring or testing apparatus or processes other than immunoassay, involving enzymes or microorganisms C12M, C12Q)
- H04N: PICTORIAL COMMUNICATION, e.g. TELEVISION
- H10F: INORGANIC SEMICONDUCTOR DEVICES SENSITIVE TO INFRARED RADIATION, LIGHT, ELECTROMAGNETIC RADIATION OF SHORTER WAVELENGTH OR CORPUSCULAR RADIATION

## Abstract

The present invention relates to a method for correcting a packaged optical sensor array module, and the method for correcting a packaged optical sensor array module according to the present invention comprises the steps of: analyzing statistical characteristics of an optical sensor array with respect to light emitted from a standard light source having a predetermined characteristic value to extract a representative value, and calculating a first correction value for a measurement value according to the extracted representative value; and calculating a second correction value for a measured value of the optical sensor array that is corrected by the first correction value with respect to light emitted from an applied light source or light emitted by a fluorescence of the applied light source.

## Claims

### Claim 1

A method for correcting an optical sensor array through characteristic evaluation, the method comprising:
setting at least one of an exposure time, an analog gain, a digital gain and a frame rate of the optical sensor array to be a default value;
statistically measuring a collection characteristic of the optical sensor array with the default value, according to a wavelength or an intensity of a standard light source having a predetermined characteristic value;
calculating a planarization calibration value for planarizing a collection characteristic value of the optical sensor array according to a wavelength change of the standard light source;
calculating a linearity calibration value for linearizing a collection characteristic value of the optical sensor array according to the intensity of the standard light source; and
performing a planarization calibration and a linearity calibration on the collection characteristics of each pixel of the optical sensor array using the planarization calibration value and the linearity calibration value.

### Claim 2 (depends on 1)

The method of claim 1, wherein the planarization calibration value or the linearity calibration value is calculated as a matrix value.

### Claim 3 (depends on 1)

The method of claim 1, wherein the statistically measuring the collection characteristic of the optical sensor array comprises measuring N times according to the set frame rate and calculating a difference between measurement values in consecutive frames among a series of the measurement values which are measured N times.

### Claim 4 (depends on 3)

The method of claim 3, wherein the statistically measuring the collection characteristic of the optical sensor array comprises calculating a difference between a measurement value of a dark frame measured without the standard light source and measurement values among the series of the measurement values which are measured N times using the measurement value of the dark frame as a reference offset value.

### Claim 5 (depends on 3)

The method of claim 3, wherein the calculating the planarization calibration value comprises determining a pixel having the highest density of the measurement values which are measured N times among all of the pixels of the optical sensor array to a reference pixel for the planarization calibration and calculating the planarization calibration value using the reference pixel for the planarization calibration.

### Claim 6 (depends on 5)

The method of claim 5, wherein the calculating the planarization calibration value comprises setting one of an average value, an intermediate value or a mode value of the reference pixel for the planarization calibration to a reference value of the planarization calibration.

### Claim 7 (depends on 1)

The method of claim 1, wherein a light intensity measurement effective range in which the measurement values linearly increase according to the intensity change of the light source with respect to at least one pixel of the optical sensor array is set.

### Claim 8 (depends on 1)

The method of claim 1, wherein the statistically measuring the collection characteristic of the optical sensor array comprises extracting a representative value of each pixel of the optical sensor array, wherein the planarization calibration value or the linearity calibration value is calculated as a calibration value for the representative value.

### Claim 9 (depends on 1)

The method of claim 1, wherein the statistically measuring the collection characteristic of the optical sensor array comprises receiving a sensitivity measurement value of a calibrated photodiode with respect to the standard light source and comparing the statistical characteristics of the sensitivity measurement values and the statistical characteristics of the optical sensor array to extract the representative value.