Crystal forms of an antitumor agent and their preparation methods
AssigneeXianchang Gong
InventorXianchang Gong
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Abstract
The present invention provides two crystal forms of jervine and their preparation methods, and their application as antitumor agents. The preparation methods of these two crystal forms are simple, high yield and can be easily scaled to industry scale.
Claims10
A crystalline form of the compound Jervine of Formula 1, wherein the crystalline form is Form I, and has an X-ray powder diffraction (XRPD) pattern comprising peaks at diffraction angle 2θ(±0.20) degrees of 13.5097°, 13.7117°, 17.7732° and 14.5810° when irradiated with a Cu-Kα light source:
A crystalline form of the compound Jervine of Formula 1, wherein the crystalline form is Form II, and has an X-ray powder diffraction (XRPD) pattern comprising peaks at diffraction angle 2θ(±0.20) degrees of 8.8458°, 13.3548°, 13.6199°, 14.4729°, 14.6803°, 15.0188°, 16.3034°, 17.1282°, 20.7405° and 20.9599° when irradiated with a Cu-Kα light source:
Dependencies are inferred from the claim text.