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US 11,111,227 B2Granted
Rotigotine behenate, and manufacturing method and application thereof
AssigneeShandong Luye Pharmaceutical Co., Ltd.
InventorsMina Yang, Yongtao Jiang, Ying Meng, Tao Wang, Qian qian Xu, Xin Shao, Chunjie Sha
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Abstract
The present disclosure relates to rotigotine behenate, methods for preparing the same and use of the same for treating diseases associated with dopamine receptor. The rotigotine behenate, the structure of which is shown below, is capable of reducing fluctuation in blood drug concentrations, improving the bioavailability of the drug in vivo, and achieving smooth and extended release of rotigotine.
Claims7
Rotigotine behenate, as shown in formula:
- having melting point 48-52° C.
Dependencies are inferred from the claim text.